The winner of this game has about a 99% chance of representing the Big 10 in the College Football Playoff, barring some sort of miracle by Wisconsin. Last year, the powerful defense of Michigan State stifled the high-powered Ohio State offense to clinch a birth to the Rose Bowl and Ohio State will be looking for revenge. Braxton Miller will have his hands full with Shilique Calhoun in his face and Trae Waynes and Kurtis Drummond in the secondary, while Noah Spence, Aldolphus Washington and Joey Bosa look to make Connor Cook’s life a living hell.
3. Stanford at Oregon, November 1st
A matchup that will likely go a long way in determining the winner of the Pac 12. Quite frankly, this matchup will be a great deal like the Oregon-MSU match up and Oregon is fortunate to have both games in Autzen Stadium. Oregon has experience on both sides of the ball and the play of Oregon cornerback Ifo Ekpre-Olomu could likely determine this game. If he can shut down Stanford wide receiver Ty Montgomery, the Cardinal will be in some trouble.